Researchers at the UC Davis MIND Institute are examining changes in the brain and cognition associated with aging, in males with the fragile X premutation compared to those without. An important aspect of this work is to understand risk factors for and emergence of fragile X-associated tremor-ataxia syndrome (FXTAS).

Who can participate?

Males of any ethnic background who:

  • Are older than 45 years old
  • Are carriers of the Fragile X premutation and live in North America,


  • Are not carriers of the Fragile X premutation and live in Northern California

What does the study involve?

  • Two 2-day visits to the MIND Institute over 5 years
  • Medical history exam
  • Neuropsychological and neurological assessments
  • MRI and blood draw

What else can be expected?

  • Upon request, families will receive feedback about cognitive strengths and weaknesses
  • You will receive compensation for your time and reimbursement of travel expenses to attend clinic visits
  • You will receive a picture of your brain
  • FXTAS symptoms and other clinical problems, if they emerge, are monitored and appropriate referrals are provided

About the MIND Institute

The UC Davis MIND Institute is a collaborative international research center, committee to the awareness, understanding, prevention, and care of neurodevelopmental disorders. All studies take place at:

MIND Institute
2825 50th Street
Sacramento, California, 95817

Visit or more information.


If you’d like to learn more or apply for this opportunity, please fill out the form to send your contact information to the study coordinator or you may contact Glenda Espinal directly at (916) 703-0470 or

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