Researchers at the UC Davis MIND Institute are examining changes in the brain and cognition associated with aging, in males with the fragile X premutation compared to those without. An important aspect of this work is to understand risk factors for and emergence of fragile X-associated tremor-ataxia syndrome (FXTAS).
Who can participate?
Males of any ethnic background who:
- Are older than 45 years old
- Are carriers of the Fragile X premutation and live in North America,
or
- Are not carriers of the Fragile X premutation and live in Northern California
What does the study involve?
- Two 2-day visits to the MIND Institute over 5 years
- Medical history exam
- Neuropsychological and neurological assessments
- MRI and blood draw
What else can be expected?
- Upon request, families will receive feedback about cognitive strengths and weaknesses
- You will receive compensation for your time and reimbursement of travel expenses to attend clinic visits
- You will receive a picture of your brain
- FXTAS symptoms and other clinical problems, if they emerge, are monitored and appropriate referrals are provided
About the MIND Institute
The UC Davis MIND Institute is a collaborative international research center, committee to the awareness, understanding, prevention, and care of neurodevelopmental disorders. All studies take place at:
MIND Institute
2825 50th Street
Sacramento, California, 95817
Visit mindinstitute.ucdavis.edu or more information.
If you’d like to learn more or apply for this opportunity, please fill out the form to send your contact information to the study coordinator or you may contact Glenda Espinal directly at (916) 703-0470 or HS-TrajectoriesStudy@ucdavis.edu.
Our Most Recent Opportunities
Assessing Parental/Guardian Experiences with Genetic Counseling for Fragile X Syndrome
Molly Mizenko, a student researcher in Indiana University’s Genetic Counseling Graduate Program, is conducting a survey to explore the experiences of parents and guardians who have received genetic counseling following their child’s diagnosis of Fragile X syndrome.
Study: Examining Factors that Influence Expectations for Individuals with an Intellectual or Developmental Disability (IDD)
Dr. Grace Francis from George Mason University is conducting an online survey to explore factors that affect the expectations for individuals with intellectual or developmental disabilities (IDD), including Fragile X syndrome (FXS), after they finish school.
Study: Identifying Translational Sleep Biomarkers in Autism
The Manoach Lab at Massachusetts General Hospital is conducting a research study to explore brain activity during sleep and sensory processing in individuals living with Fragile X syndrome (FXS).
Single-Dose Study for Adult Men with FXS
Cincinnati Children's Hospital Medical Center is looking for males ages 18-40 with FXS to participate in a single-dose clinical trial that is studying a drug called Gaboxadol.
Study: Somatic symptom development in 6-12 year old females with an FMR1 mutation (SoS Study)
Researchers at the New York State Institute for Basic Research are conducting a study to better understand the development of physical (somatic) symptoms in females living with and without an FMR1 gene variation.
Study: Web Intervention for Parents of Youth with Genetic Syndromes (WINGS)
Researchers at the Autism Assessment, Research, Treatment & Services (AARTS) Center at Rush University Medical Center are currently conducting a fully-virtual research study that is testing two telehealth interventions that are designed to help parents of children with genetic syndromes and intellectual disabilities gain strategies to manage challenging behaviors.