Researchers at the UC Davis MIND Institute are examining changes in the brain and cognition associated with aging, in males with the fragile X premutation compared to those without. An important aspect of this work is to understand risk factors for and emergence of fragile X-associated tremor-ataxia syndrome (FXTAS).
Who can participate?
Males of any ethnic background who:
- Are older than 45 years old
- Are carriers of the Fragile X premutation and live in North America,
or
- Are not carriers of the Fragile X premutation and live in Northern California
What does the study involve?
- Two 2-day visits to the MIND Institute over 5 years
- Medical history exam
- Neuropsychological and neurological assessments
- MRI and blood draw
What else can be expected?
- Upon request, families will receive feedback about cognitive strengths and weaknesses
- You will receive compensation for your time and reimbursement of travel expenses to attend clinic visits
- You will receive a picture of your brain
- FXTAS symptoms and other clinical problems, if they emerge, are monitored and appropriate referrals are provided
About the MIND Institute
The UC Davis MIND Institute is a collaborative international research center, committee to the awareness, understanding, prevention, and care of neurodevelopmental disorders. All studies take place at:
MIND Institute
2825 50th Street
Sacramento, California, 95817
Visit mindinstitute.ucdavis.edu or more information.
If you’d like to learn more or apply for this opportunity, please fill out the form to send your contact information to the study coordinator or you may contact Glenda Espinal directly at (916) 703-0470 or HS-TrajectoriesStudy@ucdavis.edu.
Our Most Recent Opportunities
Study: Autonomic and Sensory Functioning in Infants with FMR1 Conditions
Dr. Jane Roberts and the research staff at the Neurodevelopmental Disorders Laboratory at USC are conducting a research study to learn about the development of infants with Fragile X syndrome and Fragile X premutation over the first few years of life.
Survey: Research experiences in Fragile X Families
The Brain and Biomarker Lab at the University of Oklahoma is conducting a survey to learn about experiences with research, particularly biomedical research, in families with Fragile X syndrome (FXS).
Study: Language Study for Children and Adolescents with Fragile X syndrome
Researchers at the University of Wisconsin-Madison and the University of Massachusetts-Amherst are conducting a study to learn about links between learning and language in Fragile X syndrome.
Survey: Fragile X Nutrition Survey
The University of Wisconsin-Madison is conducting a survey to learn about associations between infant feeding and neurodevelopment in children with Fragile X syndrome.
Clinical Trial: Phase 2B/3 Studies of BPN14770 in Fragile X syndrome
Tetra Therapeutics is conducting a two randomized, placebo-controlled studies of BPN14770/zatolmilast to learn about the experimental drug’s safety and efficacy for males ages 12-45.
Survey: Developing a Gold Standard for Tracking Adult Functional Outcomes in Developmental Disabilities (AFS Study)
University of Pittsburgh is conducting this research to develop the Adult Functioning Scale (AFS), a new survey being designed to capture outcomes in the areas of social functioning, employment, independence, and satisfaction for individuals with various developmental disorders.