Fragile X Syndrome & Autism
Families and some providers are often confused by the relationship between Fragile X syndrome and autism. It is important to note that it is more common for a child to be diagnosed with autism first and receive an additional diagnosis of FXS. There are overlaps and gaps between the two conditions, and understanding these distinctions can be particularly helpful when deciding on the most appropriate medical, therapeutic, and education interventions, and will increase the potential for both short- and long-term benefits.
- Understanding Autism Spectrum Disorder in Fragile X Syndrome — Treatment Recommendation
- Webinars
- From Our Blog
- Additional Resources
Treatment Recommendations
The NFXF’s family-friendly Treatment Recommendations are in-depth documents developed by NFXF staff, members of the NFXF’s Fragile X Clinical & Research Consortium (FXCRC), and other Fragile X professionals, and reviewed and edited by the entire FXCRC.
Fragile X Syndrome and autism can be confusing for families. This consensus helps explain how they can overlap and how to get the best treatment for them, plus advice from experts on how to help individuals with Fragile X Syndrome and autism.
Webinars
Autism Spectrum Disorder in Fragile X Syndrome: Co-Occurring Conditions and Current Treatment — Webinar
Individuals with a dual diagnosis of Fragile X syndrome and autism have reported greater cognitive and behavioral impairment. With Dr. Walter E. Kaufmann.
Letʼs Talk Fragile X Syndrome, Autism & Behavior — Webinar Replay
Developmental FX joins us to provide insight and advice on Fragile X and its connection to autism and behavior.
From Our Blog
FXS and ASD: Similar But Different
This discussion provides clinical perspectives on the behavioral differences between FXS and what are thought to be core features of autism. There is still much to be learned about identifying behaviors that suggest the presence or absence of ASD in FXS.
A Blood Test for Autism? Not So Fast
Among families and professionals, in schools and therapeutic settings, there is already a great deal of confusion about the relationship between genetic test results and developmental diagnoses. We challenge the the notion that autism itself can be directly diagnosed through a blood test.
Doggone It … Mantras Are Great for Learning!
Mantras, like positive affirmations, really do have power. Mantras are short, positive, instructive statements full of action words. We use them to quiet the mind and focus on thinking and action.
Adapting Autism Interventions for Fragile X Syndrome
Fragile X experts Sarah K. Scharfenaker and Tracy Stackhouse discuss how to adapt autism interventions for those with Fragile X syndrome.
Additional Resources
Delineating Repetitive Behavior Profiles Across the Lifespan in Fragile X Syndrome
More research is needed to develop a deeper understanding of the effect IQ, gender, and ASD diagnosis have on the RRB profile of individuals with FXS and inform treatment. Looking at these behaviors over time may help professionals understand changes in RRBs in individuals with FXS over time.
ASD Diagnosis in Fragile X Syndrome
This research suggests there are differences between the diagnosis of FXS and FXS+ASD. More work needs to be done to examine additional modifications, beyond the deletion of non-informative items, that can further improve the diagnostic potential of the SCQ and SRS in FXS.
Behavioral Issues in FXS+ASD
While parents may be well aware of the differences between FXS, ASD, and FXS+ASD, teachers, clinicians, and other professionals, need to understand that FXS+ASD isn’t merely a sum of its parts.