Dr. Kathryn Argue Shares Information and Tips for Applying for DOD’s PRMRP Funding
The NFXF hosted a webinar featuring Dr. Kathryn Argue, Deputy Program Manager of the Peer Reviewed Medical Research Program. Dr. Argue shared information reviewing the details of the Congressionally Directed Medical Research Program, specifically the Peer-Reviewed Medical Research Program (PRMRP). Thanks to the efforts of the NFXF advocates, Fragile X, which includes all FMR1-associated conditions and disorders (FXS, FXTAS, FXPOI, Fragile X Premutation), is once again included as an eligible topic area for Fiscal Year 25 (FY25).
Dr. Argue shared programmatic details, deadlines, and tips to support researchers throughout the application process, and answered questions from attendees.
Key takeaways include:
- Align your proposal with the program-specific goals
- Review the FY25 PRMRP Synopsis of Award Mechanisms Table
- Fragile X sits in the Rare Diseases and Conditions Portfolio
- Review the specific Strategic Goals for FY 25
- Applications must address one Strategic Goal and one Topic Area
- More information can be found here: Research Funding Opportunity from CDMRP/PRMRP for Fiscal Year 25 | NFXF (fragilex.org)
A few top tips from Dr. Argue include:
- Read the funding opportunity announcement carefully
- Address Military Relevance and Impact in your application
- Funding opportunities require a Letter of Intent (LOI) due June 9, 2025 @ 5 PM ET (An invitation is not required)
- The full application deadline is July 21, 2025, @ 11:59 PM ET
- Applicants who conduct research at institutions around the world are eligible to submit an application
- Sign up for the listserv through the CDMRP website or eBRAP
Watch a recording of the webinar below.
We are grateful for partners like the PRMRP who fund Fragile X research. Thank you, Dr. Argue, for taking the time to educate us about this valuable funding opportunity. If you have questions about the PRMRP, please email help@ebrap.org.
The NFXF is also here to help! If you would like to participate in the NFXF’s Research Readiness Program, consult with our Family Advisory Commitee, or partner in another way, please reach out to anna@fragilex.org.
about

Missy Zolecki
Missy joined NFXF team in 2018 after being an active volunteer since 2010. Missy organized several fundraisers and educational workshops while serving in her volunteer role. Missy is the mother of three children. Her eldest son, Matt, lives with Fragile X syndrome. Prior to joining the NFXF team, Missy had worked as a nurse for more than 20 years. She enjoys traveling and spending time with family and friends.
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Inhibition Deficits Are Modulated by Age and CGG Repeat Length in Carriers of the FMR1 Premutation Allele Who Are Mothers of Children with Fragile X Syndrome
RESEARCH RESULTS ROUNDUP — Older mothers of children with Fragile X syndrome who have mid-range CGG repeats (~80–100) may be at increased risk for difficulties with inhibition.
Language Across the Lifespan in Fragile X Syndrome: Characteristics and Considerations for Assessment
RESEARCH RESULTS ROUNDUP — Describe cognition and language in FXS using the data from a large group, while trying to understand if the standard assessments are feasible (able to be done accurately) and valid (reflect reality) in FXS and then compared the assessment results to caregiver report.