Individuals with the Fragile X premutation are at an increased risk for depression, other psychiatric conditions, and developing Fragile X tremor/ataxia syndrome (FXTAS). Our goal is to better understand the different mechanisms within the brain that contribute to the development of psychiatric conditions, including depression. Doing so will allow us to establish better prevention and intervention efforts within this population.
Q: Who can take part in this study?
We are currently recruiting females between 18-60 who carry the FMR1 premutation.
Q: What will participation involve?
Participation involves four types of data collection:
- Web-based questionnaires.
- In-person assessments that involve responding quickly to shapes and viewing emotional stimuli.
- Gathering a variety of biological measurements such as brain activity (EEG and/or MRI), heart rate activity, and a blood draw.
- Interviews about your feelings and experiences.
Q: How will this project help the Fragile X community?
We hope that our data will impact the broader community of individuals with the Fragile X premutation and depression by improving our understanding of brain mechanisms and treatment needs.
Q: Will I need to travel?
All assessments and tests for this study are done in person and at Purdue in West Lafayette, Indiana. Travel reimbursement may be available for folks who are commuting more than 45 minutes from the Purdue campus.
Q: How can I get more information?
This project is led by Dr. Dan Foti and Dr. Bridgette Tonnsen in the Department of Psychological Sciences at Purdue University. To learn more, please complete the form below and they will contact you.
This study is funded by Purdue University and the Indiana Clinical & Translational Sciences Institute. Photo courtesy of Matthew Thomas of Purdue University.
NOTE: This study is not currently recruiting individuals.
Our Most Recent Opportunities
Study: Aging in Mothers who Carry the FMR1 Premutation
The University of South Carolina is conducting a research study to learn about healthy aging in women who carry the FMR1 premutation.
Study: iBehavior- A Novel Behavior Tracking App Study for individuals with Fragile X syndrome
The T-PAL Lab at the UC Davis MIND Institute is conducting a research study to learn about how we can best measure your child’s behavioral and cognitive functioning in their day-to-day life. Using an iPhone or Android based mobile app at your convenience, you will record your child’s behavior daily for up to 3 weeks. About the Study Who can participate? Parents with a child 5-17 years old with a [...]
Study: Transitioning to Adulthood with Fragile X syndrome
University of Kansas’ LifeSpan Institute is conducting research to learn about the transition to adulthood for individuals with Fragile X syndrome, as well as the experiences of parents of these young adults.
Study: Autonomic and Sensory Functioning in Infants with FMR1 Conditions
Dr. Jane Roberts and the research staff at the Neurodevelopmental Disorders Laboratory at USC are conducting a research study to learn about the development of infants with Fragile X syndrome and Fragile X premutation over the first few years of life.
Survey: Research Experiences in Fragile X Families
The Brain and Biomarker Lab at the University of Oklahoma is conducting a survey to learn about experiences with research, particularly biomedical research, in families with Fragile X syndrome (FXS).
Study: Language Study for Children and Adolescents with Fragile X syndrome
Researchers at the University of Wisconsin-Madison and the University of Massachusetts-Amherst are conducting a study to learn about links between learning and language in Fragile X syndrome.