Researchers at the UC Davis MIND Institute are examining changes in the brain and cognition associated with aging, in males with the fragile X premutation compared to those without. An important aspect of this work is to understand risk factors for and emergence of fragile X-associated tremor-ataxia syndrome (FXTAS).
Who can participate?
Males of any ethnic background who:
- Are older than 45 years old
- Are carriers of the Fragile X premutation and live in North America,
or
- Are not carriers of the Fragile X premutation and live in Northern California
What does the study involve?
- Two 2-day visits to the MIND Institute over 5 years
- Medical history exam
- Neuropsychological and neurological assessments
- MRI and blood draw
What else can be expected?
- Upon request, families will receive feedback about cognitive strengths and weaknesses
- You will receive compensation for your time and reimbursement of travel expenses to attend clinic visits
- You will receive a picture of your brain
- FXTAS symptoms and other clinical problems, if they emerge, are monitored and appropriate referrals are provided
About the MIND Institute
The UC Davis MIND Institute is a collaborative international research center, committee to the awareness, understanding, prevention, and care of neurodevelopmental disorders. All studies take place at:
MIND Institute
2825 50th Street
Sacramento, California, 95817
Visit mindinstitute.ucdavis.edu or more information.
If you’d like to learn more or apply for this opportunity, please fill out the form to send your contact information to the study coordinator or you may contact Glenda Espinal directly at (916) 703-0470 or HS-TrajectoriesStudy@ucdavis.edu.
Our Most Recent Opportunities
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Cincinnati Children's Hospital Medical Center is looking for males ages 18-40 with FXS to participate in a single-dose clinical trial that is studying a drug called Gaboxadol.
Study: Somatic symptom development in 6-12 year old females with an FMR1 mutation (SoS Study)
Researchers at the New York State Institute for Basic Research are conducting a study to better understand the development of physical (somatic) symptoms in females living with and without an FMR1 gene variation.
Study: Web Intervention for Parents of Youth with Genetic Syndromes (WINGS)
Researchers at the Autism Assessment, Research, Treatment & Services (AARTS) Center at Rush University Medical Center are currently conducting a fully-virtual research study that is testing two telehealth interventions that are designed to help parents of children with genetic syndromes and intellectual disabilities gain strategies to manage challenging behaviors.
Neural Underpinnings of the Relationship Between Cognition and Gait Dysfunction in Fragile X-Associated Tremor/Ataxia Syndrome (FXTAS)
Movement disorders researchers at Rush University Medical Center are conducting a research study to learn about brain activation in people living with FXTAS during tasks like walking and thinking. This study is currently recruiting adults ages 50+ who are living with FXTAS.
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Researchers at the University of Alabama are looking for members of the FX community to take their online survey so they can explore the knowledge & opinions of the FXS community on pharmacogenomic testing.