Cincinnati Children’s Hospital Medical Center is conducting a unique clinical trial involving just a single dose. The study will explore the effects of Gaboxadol and its potential to alter the brain’s response to sound. Additionally, this trial will assess the feasibility of conducting research assessments from the comfort of participants’ homes.
About the Study
Who can participate?
Adult men ages 18-40 years old with a diagnosis of Fragile X syndrome may be eligible to participate.
What will happen in the study?
If the individual qualifies and decides to participate in this research study, they will complete a total of 4 visits over the course of 8 weeks. 2 of the visits are completed at Cincinnati Children’s Hospital Medical Center and 2 visits are completed in the participant’s home.
The following is a list of some of the things that will happen during the study:
- Blood draws
- EEG tasks
- Cognitive testing
- Neuropsychological games
- Parent-reported measures
What are the good things that can happen from this research?
We cannot promise any benefits to you or others from your taking part in this research. We hope the information learned from this study will benefit others with FXS in the future. Information gained from this research could lead to better treatments for FXS.
What are the bad things that can happen from this research?
There are minimal risks associated with Gaboxadol. These include: drowsiness, headache and nausea. However, the study team will take all necessary precautions to minimize these risks.
There may be other risks that we do not know about yet.
Will I or my child be paid to complete this study?
Participants receive $100 at every visit ($400 total). Travel reimbursement may be available for eligible families.
Interested in Participating?
Our Most Recent Opportunities
Assessing Parental/Guardian Experiences with Genetic Counseling for Fragile X Syndrome
Molly Mizenko, a student researcher in Indiana University’s Genetic Counseling Graduate Program, is conducting a survey to explore the experiences of parents and guardians who have received genetic counseling following their child’s diagnosis of Fragile X syndrome.
Study: Examining Factors that Influence Expectations for Individuals with an Intellectual or Developmental Disability (IDD)
Dr. Grace Francis from George Mason University is conducting an online survey to explore factors that affect the expectations for individuals with intellectual or developmental disabilities (IDD), including Fragile X syndrome (FXS), after they finish school.
Study: Identifying Translational Sleep Biomarkers in Autism
The Manoach Lab at Massachusetts General Hospital is conducting a research study to explore brain activity during sleep and sensory processing in individuals living with Fragile X syndrome (FXS).
Single-Dose Study for Adult Men with FXS
Cincinnati Children's Hospital Medical Center is looking for males ages 18-40 with FXS to participate in a single-dose clinical trial that is studying a drug called Gaboxadol.
Study: Somatic symptom development in 6-12 year old females with an FMR1 mutation (SoS Study)
Researchers at the New York State Institute for Basic Research are conducting a study to better understand the development of physical (somatic) symptoms in females living with and without an FMR1 gene variation.
Study: Web Intervention for Parents of Youth with Genetic Syndromes (WINGS)
Researchers at the Autism Assessment, Research, Treatment & Services (AARTS) Center at Rush University Medical Center are currently conducting a fully-virtual research study that is testing two telehealth interventions that are designed to help parents of children with genetic syndromes and intellectual disabilities gain strategies to manage challenging behaviors.