This research seeks to understand how protein formation in the brain is affected in Fragile X syndrome (FXS). Researchers will measure the rate at which the brain makes proteins (protein synthesis) and will identify specific parts of the brain affected in FXS. In the future, measurement of protein synthesis in FXS may help us to develop and test new therapies.

The study enrolls eligible young men with FXS, ages 18-24, from around the world, and includes:

  • One visit, lasting several days, to the NIH Clinical Center, in Bethesda, Maryland.
  • Assessment by physicians
  • Blood draw, Two brain scans (PET & MRI), possible sedation
  • Travel, food, and lodging are covered and include the patient and one or two accompanying family members.
  • Compensation is paid for your time and assistance.

Please consider enrolling your child in our clinical research study of FXS. If you would like to participate, be on our mailing list, be contacted in case of future studies, or would simply like to have more information: Please call Inna Loutaev, 301-496-4707, or E-mail, or visit our website:

Department of Health & Human Services, National Institutes of Health, National Institute of Mental Health, 06-M-0214