We are excited to share journal publications like this one resulting from FORWARD data. There are many more papers currently in development, and the future for Fragile X syndrome research is bright as more data is gathered.
A study on height and body mass index in Fragile X syndrome suggested that height growth decreases with age and is slightly but significantly lower than the general population by adulthood. Weight and BMI increased with age and were quite a bit higher than the general population by adulthood. Antipsychotic use was associated with higher BMI, while stimulants and anticonvulsants were associated with lower BMI. This suggests that the deficit in physical activity in Fragile X syndrome identified in FORWARD may play a role in high BMI.
Choo, T-H, Xu, Q, Budimirovic, D, et al. Height and BMI in fragile X syndrome: A longitudinal assessment. Obesity (Silver Spring). 2022; 30: 743– 750. doi:10.1002/oby.23368
About the FORWARD Registry & Database
FORWARD is made possible by all the participating families sharing their life experiences for research. By giving families, doctors, scientific researchers, and policymakers an inside look into how Fragile X syndrome presents itself across the human lifespan, you’re involvement is a huge contribution toward more positive health outcomes and better care and services for future generations.
Below are more journal publications resulting from FORWARD data.
more from forward
Latent Class Analysis Identifies Distinctive Behavioral Subtypes in Children with Fragile X Syndrome
FORWARD // Among the different models resulting from the latent class analysis, a 5-class solution yielded the most clinically meaningful pharmacotherapy-independent behavioral subtypes.
Examination of Correlates to Health-Related Quality of Life in Individuals with Fragile X Syndrome
FORWARD // We examined the nature and degree of association between health-related quality of life and established measures of functioning in FXS; 155 parents completed the questionnaires on their child as part of the larger CDC-funded FORWARD study.