Medication

Many individuals with Fragile X syndrome (FXS) exhibit delays in development and can also have challenging behaviors, both of which can impact academic and daily functioning. Medications are at times helpful to facilitate the individual’s ability to attain optimal life skills and allow for better integration into educational, adult, and social environments.

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    Many individuals with Fragile X syndrome (FXS) exhibit delays in development and can also have challenging behaviors, both of which can impact academic and daily functioning. Medications are at times helpful to facilitate the individual’s ability to attain optimal life skills and allow for better integration into educational, adult, and social environments.
     

    Medications in Fragile X Syndrome

    Medication treatment in Fragile X syndrome is recommended in appropriate individuals as a treatment to be used in conjunction with therapeutic services, including:

    • Behavioral intervention
    • Speech and language therapy
    • Occupational therapy
    • Individualized educational support

    It is also important to set up the environment, to the extent possible, for success. Examples might include:

    • Setting up a routine
    • Using visual schedules
    • Allowing time for transitions
    • Minimizing sensory stimuli

    There are several common symptoms and psychiatric conditions in individuals with Fragile X syndrome that are treated with the same medications used in the general population and in individuals with other developmental disabilities. These medications have been reported to be effective for individuals with Fragile X syndrome in retrospective clinical studies.

    It’s important to note that there is limited formal research or clinical trial data to demonstrate the best approach to the use of medication specifically in individuals with Fragile X syndrome. Any medication use should be discussed with and under the supervision of a doctor and tailored to the individual’s needs.

    Learn more about specific medications recommended to treat various symptoms of Fragile X syndrome by reviewing the Treatment Recommendation. You can search by navigated by medication name or area of concern.

    Treatment Recommendations

    Medications for Individuals with Fragile X Syndrome

    Medications are, at times, helpful to facilitate the individual’s ability to attain optimal life skills and allow for better integration into educational, adult, and social environments.

    Clinical Trials on Medications

    Clinical trials are research studies that test an intervention or possible treatment in people and are the main way of determining if a new form of treatment, like a new drug, is safe and effective in people. (The Basics | National Institutes of Health (NIH) There are several active clinical trials for Fragile X going on right now!

    Learn more about the active clinical trials on medications for Fragile X syndrome by visiting their MyFXResearch posts:

    EXPERIENCE Clinical Trials in Fragile X Syndrome

    Clinical Trial RECONNECT: Zyn002 Gel

    References