Sleep Problems in FXS: Cross-Sectional Analysis of a Large Clinic-Based Cohort
Previous studies have shown that children with Fragile X syndrome exhibit a higher frequency of sleep problems relative to typically developing counterparts. This paper[1] describes an overview of sleep difficulties in children with FXS and their impact on families. The Fragile X Online Registry with Accessible Research Database (FORWARD), including Clinician Report and Parent Report forms, was analyzed for frequency, severity, relationship with behavioral problems, and impact of sleep difficulties in a mainly pediatric cohort.
Findings showed that sleep difficulties are prevalent in children with FXS and, although they tend to be mild, they are associated with behavioral problems and negative impact to families.
