Height and Body Mass Index in Fragile X Syndrome: A Longitudinal Assessment

Amie Milunovich
Amie Milunovich

05 mins read

We are excited to share journal publications like this that resulted from FORWARD data. Many more papers are currently being developed, and the future of Fragile X syndrome research is bright as more data is gathered. FORWARD-MARCH is the next step, and we will collect more detailed information.

A study on height and body mass index in Fragile X syndrome suggested that height growth decreases with age and is slightly but significantly lower than the general population by adulthood. Weight and BMI increased with age and were quite a bit higher than the general population by adulthood. Antipsychotic use was associated with higher BMI, while stimulants and anticonvulsants were associated with lower BMI. This suggests that the deficit in physical activity in Fragile X syndrome identified in FORWARD may play a role in high BMI.

FULL ARTICLE

Choo, T-H, Xu, Q, Budimirovic, D, et al. Height and BMI in fragile X syndrome: A longitudinal assessment. Obesity (Silver Spring). 2022; 30: 743– 750. doi:10.1002/oby.23368

About the FORWARD-MARCH Registry & Database

Since 2012, the CDC has funded FORWARD Fragile X studies to expand understanding of Fragile X syndrome. The NFXF has been coordinating study efforts since the beginning and has been vital in ensuring its success.

FORWARD-MARCH is the next step and will collect more detailed information from participants to better understand FXS and improve the lives of children and adolescents with FXS and the lives of their families.

Learn more about FORWARD-MARCH and how to participate.

About the Author

Amie Milunovich

Amie joined the NFXF in 2015. She holds a bachelor’s degree in family and consumer science and is a SOCRA certified clinical research professional (CCRP). Amie has over 15 years of experience working in clinical research. She enjoys Bikram yoga, painting, cooking, and spending time with family and friends.