The Fragile X Premutation
Learn about the Fragile X premutation, family planning resources, new developments, and more about the two associated conditions, FXTAS and FXPOI.
The Basics
What is the Fragile X Premutation?
The Fragile X premutation is one type of mutation within the Fragile X FMR1 gene. As many as 1.5 million people in the U.S. have the premutation, many unknowingly.
Reproductive Resources
Fragile X family planning resources include carrier screening, genetic counseling, reproductive options, and associated costs.
Fragile X-Associated Conditions
FXTAS
Fragile X-associated tremor/ataxia syndrome, or FXTAS, is a late-onset neurodegenerative disorder seen more commonly in males. Learn more about who should be tested, the diagnostic criteria for a diagnosis, resources, and clinic options.
FXPOI
Fragile X-associated primary ovarian insufficiency, or FXPOI, causes the ovaries to lose their normal function. Learn more about the prevelance of FXPOI, signs and symptoms, testing, and treatment options.
New Developments
Discover research currently underway to look at various issues that may be seen in people with the Fragile X premutation, and associated conditions.