The purpose of this study is to improve our understanding of how differences in brain activity affect learning, language, and behavior in children with Fragile X Syndrome (FXS). Currently, there is no effective treatment for FXS. Our goal is to find brain markers that predict cognitive, language, and behavioral difficulties in young boys with FXS, and to better understand differences in brain activity between children with and without FXS. The study is funded by FRAXA Research Foundation with additional support from the Pierce Family Fragile X Foundation and the Autism Science Foundation.
Eligibility for Study Participation
- Boys 32-66 months old with a diagnosis of Fragile X Syndrome based on full mutation of the FMR1 gene.
- Boys 32-66 months old who are typically developing.
What will you do?
- Single 4 hour visit at the Labs of Cognitive Neuroscience at Boston Children’s Hospital.
- This visit includes clinical and behavioral assessments that will evaluate your child’s thinking, motor skills, language skills, and social communication. In addition, we will measure your child’s brain activity using electroencephalography (EEG).
- EEG is a safe and radiation-free way to measure brain activity in response to different sounds and pictures.
What will you receive?
- Families will receive a small toy and $25 for participating. We will provide free parking and childcare for siblings.